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The following patents and patent applications have cited an INR® patent:

U.S. Patents citing an INR patent (partial list):

Amgen Fremont, Inc. Antibodies directed to tumor necrosis factor US patent 7,285,269
Medarex, Inc., GenMab A/S, Human monoclonal antibodies against interleukin 8 (IL-8), US patent 7,282,568
Reagents of the University of Colorado, Methods for treating neuropathic pain by administering IL-10 polypeptides, US Pat. 7261882
Depuy Spine, Inc., Autologous coatings for implants US Pat. 7217425
Applied Molecular Evolution TNF-alpha binding molecules, US patent 7,101,978
Kennedy Institute of Rheumatology, Small molecular weight TNF receptor multimeric molecule US Pat. 7070783
Schering Corp. US patent 6,838,466, Compounds for the treatment of inflammatory disorders
Pharmacia Corporation, Methods for treating glaucoma, US Pat. 6814966
The General Hospital Corporation Treatments for immune-mediated ear disorders, US Pat. 6548527

U.S. patent applications citing an INR patent (partial list):

20070172449 ­ Xencor, Inc. - Tnf-Alpha Variant Formulations For The Treatment Of Tnf-Alpha Related Disorders
20060289021 ­ Johnson & Johnson - Ultraviolet Therapies For Spine-Related Pain
20060173080 ­ Methods of modulating TNF using bupropion
20050079178 ­ David Kem and Eugene Patterson - Inhibitor of cardiac tachyarrhythmias

Medtronic, Inc.
20050180974 ­ Medtronic, Inc. - Extracellular TNF inhibitors for treating CNS disorders
20050095246 ­ Medtronic, Inc. -Techniques to treat neurological disorders by attenuating the production of pro-inflammatory mediators

DePuy Spine:
20060019869 ­ DePuy Spine, Inc. - Intradiscal anti-inflammatory therapy involving autologous adiponectin
20060130853 ­ DePuy Spine, Inc. - Ultra violet therapies for spine-related pain
20050112091 ­ DePuy Spine, Inc. - Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
20050038001 ­ DePuy Spine, Inc. -Transdiscal administration of cycline compounds
20050025765 ­ DePuy Spine, Inc. -Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
20040229878 ­ DePuy Spine, Inc. - Transdiscal administration of specific inhibitors of P38 kinase
20040228853 ­ DePuy Spine, Inc. - Transdiscal administration of high affinity anti-MMP inhibitors

Note:these lists should not be construed to imply that a business or other relationship exists between these companies and the INR.

The following publications in 2007 have cited scientific publications from the INR®:

Scientific Articles:
1. Uceyler N, Sommer C. Cytokine-induced Pain: Basic Science and Clinical Implications. Reviews in Analgesia 2007;9(2):87-103.
2. Tweedie D, Sambamurti K, Greig NH. Drug Design & Development Section, Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, US. TNF-alpha Inhibition as a Treatment Strategy for Neurodegenerative Disorders: New Drug Candidates and Targets. Curr Alzheimer Res. 2007 Sep;4(4):375-8.
2. Tubbs RS, Hansasuta A, Loukas M, Louis RG, Jr., Shoja MM, Salter EG, et al. The basilar venous plexus. Clin Anat 2007.
3. Saxena AK, Kumar S. Management strategies for pain in breast carcinoma patients: current opinions and future perspectives. Pain Pract 2007;7(2):163-77.
4. Owlia MB, Salimzadeh A, Alishiri G, Haghighi A. Comparison of two doses of corticosteroid in epidural steroid injection for lumbar radicular pain. Singapore Med J 2007;48(3):241-5.
5. Munoz L, Ralay Ranaivo H, Roy SM, Hu W, Craft JM, McNamara LK, et al. A novel p38alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model. J Neuroinflammation 2007;4(1):21.
6. Hu W, Ranaivo HR, Roy SM, Behanna HA, Wing LK, Munoz L, et al. Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits. Bioorg Med Chem Lett 2007;17(2):414-8.
7. Le Maitre CL, Hoyland JA, Freemont AJ. Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile. Arthritis Res Ther. 2007 Aug 9;9(4):R77.
Hardcover/ Bound Texts:
1. Neuroinflammation in Neuronal Death and Repair, Volume 82 (International Review of Neurobiology.) G. Bagetta, editor (Hardcover - Jul 16, 2007) Amsterdam ; Boston : Elsevier Academic Press ©2007. ISBN: 9780123739896 0123739896.
2. Interactions Between Neurons and Glia in Aging and Disease by Joao Malva, Ana Cristina Rego, Rodrigo Cunha, and Catarina Oliveira (Eds.) (Hardcover - Aug 22, 2007). 2007, Approx. 535 p., Hardcover ISBN: 978-0-387-70829-4 New York ; London : Springer, 2007.
3. Cytokines in the Genesis and Treatment of Cancer (Cancer Drug Discovery and Development) by Michael A. Caligiuri and Michael T. Lotze (Hardcover - April 20, 2007) Totowa, N.J. : Humana Press ©2007. ISBN: 9780896038202 0896038203 9781597454551 1597454559.
4. Chapter 10: Anti-TNF-alpha antibody and cancer cachexia, The ASCRS Textbook of Colon and Rectal Surgery by J.M. Church, J. Garcia-Aguilar, P.L. Roberts, and T.J. Saclarides; New York : Springer ©2007. ISBN: 9780387248462 0387248463.
5. Spinal Reconstruction: Clinical Examples of Applied Basic Science, Biomechanics and Engineering by Kai-Uwe Lewandrowski, Michael J. Yaszemski, Iain Kalfas, and Paul Park (Hardcover - Feb 12, 2007) New York : Informa Healthcare ©2007. ISBN: 9780849398155 0849398150.
6. Olesen J, Jensen T. From Basic Pain Mechanisms to Headache. Oxford University Press 2007.
7. Neuroimmunology: The Immune System and Alzheimers, in the 2007 Progress Report on Brain Research, Dana Alliance for Brain Initiatives, Dana Press, New York ©2007.


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